Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Thiosulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosulfuric Acid SCHEMBL3624543 | 1.00 | — | — | |
| Thiosulfuric Acid SCHEMBL167837 | 0.95 | — | — | |
| Thiosulfuric Acid SCHEMBL6383999 | 0.90 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL5544948 | 0.90 | MEN1 (0.46) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL8162779 | 0.90 | MEN1 (0.46) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL2022293 | 0.90 | — | — | |
| Thiosulfuric Acid SCHEMBL4626957 | 0.90 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL5309938 | 0.90 | MEN1 (0.46) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL144181 | 0.90 | — | — | |
| Thiosulfuric Acid SCHEMBL11139319 | 0.90 | MEN1 (0.46) | MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150174160-A1 | METHODS FOR TREATING, DIAGNOSING AND/OR MONITORING PROGRESSION OF OXO ASSOCIATED STATES | PRAVDA JAY (US) | 2015-06-25 | — | — | US | claimed |
| EP-2866565-A2 | METHODS FOR TREATING, DIAGNOSING AND/OR MONITORING PROGRESSION OF OXO ASSOCIATED STATES | Pravda, Jay (US) | 2015-05-06 | — | — | EP | claimed |
| WO-2014008273-A2 | METHODS FOR TREATING, DIAGNOSING AND/OR MONITORING PROGRESSION OF OXO ASSOCIATED STATES | PRAVDA JAY (US) | 2014-01-09 | — | — | WO | claimed |
| US-20080116076-A1 | METHOD AND COMPOSITION FOR DIRECT METALLIZATION OF NON-CONDUCTIVE SUBSTRATES | ENTHONE INC. (US) | 2008-05-22 | — | — | US | claimed |
| CN-117947478-B | Three-dimensional alloy anode material for magnesium ion battery and preparation method and application thereof | 华北电力大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-117947478-A | Three-dimensional alloy anode material for magnesium ion battery and preparation method and application thereof | 华北电力大学 | 2024-04-30 | — | — | CN | disclosed |
| WO-2019164984-A1 | TOPICAL COMPOSITIONS WITH STABLE SOLUBILIZED SELECTIVE RETINOIDS AND/OR TETRACYCLINE-CLASS ANTIBIOTICS | BioPharmX, Inc. (US) | 2019-08-29 | — | — | WO | disclosed |
| US-20190255078-A1 | TOPICAL COMPOSITIONS WITH STABLE SOLUBILIZED SELECTIVE RETINOIDS AND/OR TETRACYCLINE-CLASS ANTIBIOTICS | LEO PHARMA A/S (DK) | 2019-08-22 | — | — | US | disclosed |
| CN-107033037-B | Asymmetric synthesis method of optical pure terpene alkaloid analogue catalyzed by chiral acid | 江西师范大学 | 2019-03-22 | — | — | CN | disclosed |
| US-RE46913-E1 | Optical brightening compositions | ARCHROMA IP GMBH (CH) | 2018-06-26 | — | — | US | disclosed |
| EP-2260145-B3 | IMPROVED OPTICAL BRIGHTENING COMPOSITIONS | CLARIANT FINANCE BVI LTD (VG) | 2017-11-01 | — | — | EP | disclosed |
| CN-107033037-A | Asymmetric synthesis method of optical pure terpene alkaloid analogue catalyzed by chiral acid | 江西师范大学 | 2017-08-11 | — | — | CN | disclosed |
| US-20040209011-A1 | Ink-jet recording material suitable for pigment ink | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 2004-10-21 | — | — | US | disclosed |
| US-20010012556-A1 | Ink-jet recording material suitable for pigment ink | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 2001-08-09 | — | — | US | disclosed |
| EP-1122084-A1 | Ink-jet recording material suitable for pigment ink | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0767201-B1 | Sulfur vulcanizable rubber containing hydrated thiosulfate | GOODYEAR TIRE & RUBBER (US) | 2000-05-10 | — | — | EP | disclosed |
| US-5744552-A | BLEND CONTAINING SULFENAMIDE AND HYDRATED THIOSULFATE; HEATING | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0829508-A1 | Sulfur vulcanizable rubber containing hydrated thiosulfate | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| EP-0767201-A1 | Sulfur vulcanizable rubber containing hydrated thiosulfate | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-04-09 | — | — | EP | disclosed |
| US-5594052-A | OR OTHER HYDRATED THIOSULFATE, AND A SULFENAMIDE; INCREASING RATE OF VULCANIZATION OF THE RUBBER BY HEATING WITH THE ADDITIVES; THE VULCANIZED RUBBER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190255078-A1 | TOPICAL COMPOSITIONS WITH STABLE SOLUBILIZED SELECTIVE RETINOIDS AND/OR TETRACYCLINE-CLASS ANTIBIOTICS | RARA, RARB, TST | MEN1 3200/4885ALDH1A1 1205/4885TSHR 1366/4885 |
| US-20150174160-A1 | METHODS FOR TREATING, DIAGNOSING AND/OR MONITORING PROGRESSION OF OXO ASSOCIATED STATES | OAT, OTC, HOGA1 | MEN1 3440/4885ALDH1A1 885/4885TSHR 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.