Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20358129 | 0.85 | THRB (0.45) | THRBTHRA | |
| SCHEMBL5680993 | 0.78 | CASP1 (0.47) | — | |
| SCHEMBL6249693 | 0.76 | CASP1 (0.51) | CA2 | |
| SCHEMBL995712 | 0.76 | CYP1A2 (0.51) | CA2 | |
| SCHEMBL997994 | 0.76 | CASP1 (0.48) | CA2 | |
| SCHEMBL27871822 | 0.76 | LPAR1 (0.48) | — | |
| SCHEMBL3371631 | 0.75 | CYP3A4 (0.49) | THRBTHRA | |
| SCHEMBL5679392 | 0.75 | CASP1 (0.58) | — | |
| SCHEMBL7386055 | 0.75 | TRPV4 (0.46) | — | |
| SCHEMBL30307015 | 0.75 | TRPV4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932600-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1$g(b) CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016504-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1β CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |