SCHEMBL8431300

SCHEMBL8431300

CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)C(N)=O

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 3/20 0.68
▸ CA1 P00915 1/20 0.68
▸ GRIK1 P39086 2/20 0.55
▸ GRIK2 Q13002 2/20 0.55
▸ SLC1A2 P43004 1/20 0.52
▸ SLC1A1 P43005 1/20 0.52
▸ GPR84 Q9NQS5 7/20 0.50
▸ FFAR1 O14842 1/20 0.50
▸ EPHX1 P07099 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ LCK P06239 1/20 0.48
▸ PPARD Q03181 1/20 0.48
▸ ZDHHC20 Q5W0Z9 1/20 0.48
▸ ZDHHC2 Q9UIJ5 1/20 0.48
▸ LAP3 P28838 1/20 0.47
▸ MAPK1 P28482 1/20 0.46
▸ FFAR4 Q5NUL3 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11568935 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL1858066 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL15156061 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL2090530 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL6062388 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL8430831 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL9932211 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL4603716 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL20746502 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2
SCHEMBL376410 1.00 CA2 (0.68) CA2CA1GRIK1GRIK2SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125681-A1 DOUBLE-STRANDED RNAi AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF HANGZHOU TIANLONG PHARMACEUTICAL CO., LTD. (CN) 2026-05-07 — — US claimed
EP-4736848-A1 PHARMACEUTICAL COMPOSITION CONTAINING CATIONIC LIPID AND USE THEREOF Shanghai Regenelead Therapies Co., Ltd. (CN) 2026-05-06 — — EP claimed
US-20260069541-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF ACTIVE AGENTS INCLUDING NUCLEIC ACIDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US claimed
US-12551500-B2 C6′-substituted locked nucleic acid-modified cap analog and use thereof HANGZHOU TIANLONG PHARMACEUTICAL CO., LTD. (CN) 2026-02-17 — — US claimed
EP-4688003-A2 LIPOSOMAL COMPOSITIONS OF ARCHEXIN The Whiteoak Group, Inc. (US) 2026-02-11 — — EP claimed
US-12545637-B2 Extrahepatic targeted cationic lipid compound with high efficiency and low toxicity and its composition BEIJING YOUCARE KECHUANG PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-02-10 — — US claimed
EP-4681728-A2 HERPES ZOSTER MRNA VACCINE, PREPARATION METHOD THEREFOR, AND USE THEREOF Hangzhou Tianlong Pharmaceutical Co., Ltd. (CN) 2026-01-21 — — EP claimed
US-20260014244-A1 RESPIRATORY SYNCYTIAL VIRUS MRNA VACCINE, AND PREPARATION METHOD THEREFOR AND USE THEREOF HANGZHOU TIANLONG PHARMACEUTICAL CO LTD (CN) 2026-01-15 — — US claimed
EP-4678747-A2 DOUBLE-STRANDED RNAI AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF Hangzhou Tianlong Pharmaceutical Co., Ltd. (CN) 2026-01-14 — — EP claimed
EP-4678741-A1 RESPIRATORY SYNCYTIAL VIRUS MRNA VACCINE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Hangzhou Tianlong Pharmaceutical Co., Ltd. (CN) 2026-01-14 — — EP claimed
WO-2023070132-A1 IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER OHIO STATE INNOVATION FOUNDATION (US) 2023-04-27 — — WO claimed
WO-2023070133-A2 COMPOSITIONS AND METHODS OF THE DELIVERY OF ACTIVE AGENTS INCLUDING NUCLEIC ACIDS OHIO STATE INNOVATION FOUNDATION (US) 2023-04-27 — — WO claimed
WO-2023057574-A2 INDICATIONS FOR ANTI PRAME BINDERS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2023-04-13 — — WO claimed
CN-115927480-A Gene delivery system based on nucleic acid nanostructure and preparation method and application thereof 国家纳米科学中心 2023-04-07 — — CN claimed
CN-115867654-A RNA constructs and uses thereof 生物技术欧洲股份公司 2023-03-28 — — CN claimed
CN-115811986-A Coronavirus vaccine 生物技术欧洲股份公司 2023-03-17 — — CN claimed
CN-115397856-A RNA compositions targeting claudin-18.2 生物技术公司 2022-11-25 — — CN claimed
CN-113631177-A KRAS variant mRNA molecules 库瑞瓦格股份公司 2021-11-09 — — CN claimed
EP-3893909-A2 KRAS VARIANT MRNA MOLECULES CureVac AG (DE) 2021-10-20 — — EP claimed
WO-2020123300-A2 KRAS VARIANT MRNA MOLECULES ELI LILLY AND COMPANY (US) 2020-06-18 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545637-B2 Extrahepatic targeted cationic lipid compound with high efficiency and low toxicity and its composition SLC10A1, SLC10A2, LIPC CA2 1797/4885CA1 3410/4885GRIK1 3855/4885
US-12551500-B2 C6′-substituted locked nucleic acid-modified cap analog and use thereof RNMT, RNGTT, NSUN2 CA2 1828/4885CA1 3983/4885GRIK1 4501/4885
US-20260014244-A1 RESPIRATORY SYNCYTIAL VIRUS MRNA VACCINE, AND PREPARATION METHOD THEREFOR AND USE THEREOF UPF1, SFPQ, SRSF1 CA2 4317/4885CA1 4803/4885GRIK1 3054/4885
US-20260069541-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF ACTIVE AGENTS INCLUDING NUCLEIC ACIDS PHAX, RNMT, PRKCZ CA2 2232/4885CA1 4363/4885GRIK1 1670/4885
US-20260125681-A1 DOUBLE-STRANDED RNAi AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF NSUN2, EIF2AK2, METTL16 CA2 4772/4885CA1 4740/4885GRIK1 4071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback