Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652152 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL7475308 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL2662019 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBSMN1; SMN2TDP1 | |
| SCHEMBL9819725 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL19847120 | 0.76 | NOS1 (0.42) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HTT | |
| SCHEMBL9819832 | 0.76 | MEN1 (0.68) | ALDH1A1KDM4EPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL11093397 | 0.74 | DRD2 (0.70) | ALDH1A1KDM4EPOLBSMN1; SMN2TDP1 | |
| SCHEMBL8440683 | 0.73 | SIGMAR1 (0.46) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL4466600 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL27481117 | 0.73 | FAAH (0.50) | ALDH1A1KDM4EPOLBHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097570-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | NEUROSEARCH A/S | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097570-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | GABRA1, GABRA2, GABRA4 | ALDH1A1 977/4885KDM4E 851/4885POLB 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.