Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449133 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30331254 | 0.85 | F2 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL38634 | 0.83 | CA1 (0.58) | KDM4EALDH1A1HPGDTSHRF2 | |
| SCHEMBL979896 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDTSHRF2 | |
| SCHEMBL11449132 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL38664384 | 0.82 | BCAT2 (0.42) | KDM4EALDH1A1TSHRF2PRSS1 | |
| SCHEMBL27271173 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL1498169 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL10499129 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL353392 | 0.81 | CA1 (0.63) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023095774-A1 | CHROMIUM-PLATED COMPONENT AND METHOD FOR MANUFACTURING SAME | 株式会社JCU | 2023-06-01 | — | — | WO | disclosed |
| US-5863394-A | Apparatus for electrodeposition | XEROX CORPORATION (US) | 1999-01-26 | — | — | US | disclosed |
| US-5524342-A | Methods for shrinking nickel articles | XEROX CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| US-5480528-A | Brushless electrodeposition apparatus | XEROX CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| US-5472587-A | Depositing metal on a mandrel | XEROX CORPORATION (US) | 1995-12-05 | — | — | US | disclosed |
| US-5451311-A | Endless belts incorporating thickened bands | XEROX CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
| US-5399127-A | Endless belts incorporating stiffening members | XEROX CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| US-5385660-A | Dendritic growth assisted electroform separation | XEROX CORPORATION (US) | 1995-01-31 | — | — | US | disclosed |
| US-3963587-A | Process for electroforming nickel foils | XEROX CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |