Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537398 | 0.81 | PTGIR (0.43) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL6353244 | 0.79 | CA1 (0.59) | CES2CES1ALDH1A1KMT2AGAA | |
| SCHEMBL29420501 | 0.79 | CES2 (0.44) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL6548684 | 0.79 | NOS3 (0.55) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL6350785 | 0.78 | RAB9A (0.46) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7929176 | 0.75 | RAB9A (0.50) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6357885 | 0.75 | TCF4 (0.44) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL504005 | 0.74 | L3MBTL1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL6740788 | 0.73 | ALDH1A1 (0.61) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL19505630 | 0.73 | ESR1 (0.60) | CES2CES1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235871-B1 | Synthesis of oligoarylamines, and uses and reagents related thereto | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-22 | — | — | US | disclosed |