Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550978 | 0.88 | MAPT (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL8550579 | 0.82 | NPC1 (0.35) | PTGESALOX5PPARGPLAAT3PLAAT5 | |
| SCHEMBL8554973 | 0.82 | RAB9A (0.35) | PTGESALOX5PPARGPLAAT3PLAAT5 | |
| SCHEMBL8550020 | 0.82 | GAA (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4POLB | |
| SCHEMBL8553056 | 0.81 | DNM1 (0.35) | PTGESALOX5PPARGMEN1KMT2A | |
| SCHEMBL8552707 | 0.80 | ALDH1A1 (0.52) | PLAAT3PLAAT5PLAAT2PLAAT4POLB | |
| SCHEMBL8554560 | 0.80 | LY96 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4BACE1 | |
| SCHEMBL8152247 | 0.79 | PPARG (0.42) | PTGESALOX5PPARGNQO2POLB | |
| SCHEMBL8548995 | 0.78 | ALOX5 (0.42) | PTGESALOX5PPARGPOLBMEN1 | |
| SCHEMBL8551274 | 0.78 | PLAAT3 (0.41) | PLAAT3PLAAT5PLAAT2PLAAT4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |