Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.32 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.32 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.32 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550868 | 0.88 | AKR1C3 (0.43) | NPC1ALDH1A1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8550399 | 0.87 | ALDH1A1 (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8554973 | 0.84 | RAB9A (0.35) | NPC1ALDH1A1RAB9ASMN1; SMN2PTGES | |
| SCHEMBL8554588 | 0.84 | TRPA1 (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2PTGES | |
| SCHEMBL8552707 | 0.82 | ALDH1A1 (0.52) | NPC1ALDH1A1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8544757 | 0.82 | PTGES (0.41) | ALDH1A1PTGESALOX5PPARGPLAAT3 | |
| SCHEMBL8553056 | 0.81 | DNM1 (0.35) | NPC1ALDH1A1RAB9ASMN1; SMN2PTGES | |
| SCHEMBL8550321 | 0.81 | DPEP1 (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8552779 | 0.81 | DPEP1 (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8551274 | 0.80 | PLAAT3 (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |