Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547870 | 0.89 | PDCD1 (0.43) | EGFRMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8593809 | 0.88 | FBP1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8552485 | 0.82 | ALDH1A1 (0.34) | DNM1GPR35EGFRPTGESALOX5 | |
| SCHEMBL8551609 | 0.82 | EGFR (0.39) | DNM1EGFRMAPTMEN1KMT2A | |
| SCHEMBL8544757 | 0.81 | PTGES (0.41) | PTGESALOX5PPARGMAPTMEN1 | |
| SCHEMBL8550579 | 0.81 | NPC1 (0.35) | PTGESALOX5PPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL8554973 | 0.81 | RAB9A (0.35) | PTGESALOX5PPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL8552707 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8152091 | 0.78 | APEX1 (0.36) | DNM1GPR35PTGESALOX5PPARG | |
| SCHEMBL8551274 | 0.77 | PLAAT3 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |