Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552779 | 0.90 | DPEP1 (0.41) | TRPA1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8550321 | 0.90 | DPEP1 (0.41) | TRPA1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8550399 | 0.86 | ALDH1A1 (0.41) | TRPA1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8550868 | 0.84 | AKR1C3 (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8550579 | 0.84 | NPC1 (0.35) | SMN1; SMN2ALDH1A1NPC1RAB9ARECQL | |
| SCHEMBL8551925 | 0.84 | GRIK1 (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL8554286 | 0.83 | PYGL (0.42) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8545460 | 0.82 | ALDH1A1 (0.34) | TRPA1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8551274 | 0.82 | PLAAT3 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8555352 | 0.82 | NLRP3 (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |