Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SLC26A4 | O43511 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549838 | 0.78 | ALDH1A1 (0.47) | HTR1FKMT2AMEN1ACHE | |
| SCHEMBL8547804 | 0.73 | NPC1 (0.41) | HTR1FTBK1GAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8553027 | 0.72 | NPC1 (0.40) | HTR1FGAAKMT2AMEN1HTR1A | |
| SCHEMBL8692074 | 0.71 | HPGD (0.45) | HTR1FKMT2AMEN1HTTCYP2C19 | |
| SCHEMBL8551309 | 0.69 | RAB9A (0.48) | HTR1FMTNR1AMTNR1BGAAKMT2A | |
| SCHEMBL8548295 | 0.69 | RAB9A (0.51) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL3602772 | 0.68 | LMNA (0.38) | GAAKMT2AMEN1MAOBLMNA | |
| SCHEMBL8547488 | 0.67 | HTR1F (0.53) | HTR1FKMT2AMEN1ACHELMNA | |
| SCHEMBL8549636 | 0.67 | HTR1F (0.51) | HTR1FGAAKMT2AMEN1HTR1A | |
| SCHEMBL8552580 | 0.67 | HTR1F (0.65) | HTR1FKMT2AMEN1HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |