Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.33 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554286 | 0.90 | PYGL (0.42) | DPEP1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8554588 | 0.90 | TRPA1 (0.38) | TRPA1MEN1KMT2AMAPTTP53 | |
| SCHEMBL8550321 | 0.86 | DPEP1 (0.41) | DPEP1TRPA1MEN1KMT2AMAOA | |
| SCHEMBL8551925 | 0.86 | GRIK1 (0.46) | NPC1RAB9ASMN1; SMN2PLAAT3PLAAT5 | |
| SCHEMBL8555352 | 0.84 | NLRP3 (0.46) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8549387 | 0.84 | DPEP1 (0.42) | DPEP1TRPA1MEN1KMT2AGRIK1 | |
| SCHEMBL8550399 | 0.83 | ALDH1A1 (0.41) | TRPA1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8554973 | 0.83 | RAB9A (0.35) | NPC1RAB9ASMN1; SMN2FABP4PLAAT3 | |
| SCHEMBL8550868 | 0.81 | AKR1C3 (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8550579 | 0.81 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |