Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25260549 | 0.78 | PTGES (0.62) | NFE2L2PTGESALOX5HPGDKDM4E | |
| SCHEMBL25297359 | 0.76 | ALOX5 (0.58) | NFE2L2PTGESALOX5HPGDKDM4E | |
| SCHEMBL8557510 | 0.73 | LY96 (0.55) | ALDH1A1TGM2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8157285 | 0.73 | NFE2L2 (0.44) | NFE2L2PTGESALOX5HPGDKDM4E | |
| SCHEMBL10803598 | 0.73 | SMN1; SMN2 (0.50) | HPGDKDM4EALDH1A1LMNATGM2 | |
| SCHEMBL8547091 | 0.73 | GAA (0.39) | HPGDKDM4ELMNATGM2SMN1; SMN2 | |
| SCHEMBL4845329 | 0.71 | NFE2L2 (0.56) | NFE2L2ALOX5HPGDKDM4EALDH1A1 | |
| SCHEMBL4845335 | 0.71 | NFE2L2 (0.56) | NFE2L2ALOX5HPGDKDM4EALDH1A1 | |
| SCHEMBL8547344 | 0.71 | TGM2 (0.38) | TGM2MEN1KMT2AGAA | |
| SCHEMBL8550135 | 0.70 | ALDH1A1 (0.47) | NFE2L2HPGDKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |