Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556147 | 0.96 | MAPT (0.43) | MAPTPTGES2ALDH1A1LMNARXRA | |
| SCHEMBL8557664 | 0.90 | L3MBTL1 (0.43) | MAPTALDH1A1RXRACA12CA1 | |
| SCHEMBL8557954 | 0.89 | RXRA (0.47) | MAPTALDH1A1LMNARXRACA12 | |
| SCHEMBL8560978 | 0.89 | CDK9 (0.42) | RXRACA12CA1CA2CA9 | |
| SCHEMBL8553420 | 0.87 | MAPT (0.40) | MAPTALDH1A1LMNARXRACA12 | |
| SCHEMBL8556401 | 0.87 | CYP2C9 (0.40) | MAPTPTGES2ALDH1A1LMNARXRA | |
| SCHEMBL7501551 | 0.86 | CA2 (0.43) | MAPTALDH1A1LMNACA12CA1 | |
| SCHEMBL8559042 | 0.86 | L3MBTL1 (0.43) | MAPTALDH1A1RXRACA12CA1 | |
| SCHEMBL8553816 | 0.85 | MAPT (0.40) | MAPTALDH1A1LMNARXRAP2RX3 | |
| SCHEMBL8561449 | 0.85 | RXRA (0.40) | MAPTPTGES2ALDH1A1LMNARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |