SCHEMBL861239

SCHEMBL861239

CC(C)(C)Cc1cc2nc(N)c3ccccc3c2cc1CC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DCPS Q96C86 1/20 0.36
APP P05067 3/20 0.36
TLR8 Q9NR97 3/20 0.35
DHFR P00374 2/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TLR7 Q9NYK1 2/20 0.34
ABCB1 P08183 2/20 0.34
CLK1 P49759 1/20 0.34
BACE1 P56817 1/20 0.33
NCF1 P14598 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861436 0.80 APP (0.43) DCPSAPPTLR8TLR7
SCHEMBL861842 0.78 TLR7 (0.45) DCPSAPPTLR8TLR7
SCHEMBL840325 0.73 DHFR (0.49) DCPSTLR8DHFRKDM4EALDH1A1
SCHEMBL840328 0.71 KIF11 (0.44) DCPSKDM4EALDH1A1GAAMAPT
SCHEMBL8630481 0.71 MDM4 (0.47) DCPSDHFRKDM4EALDH1A1GAA
SCHEMBL861205 0.68 CYP1A1 (0.50) DCPSAPPKDM4EALDH1A1MAPT
SCHEMBL28384000 0.68 HTR2A (0.38) ALDH1A1HPGDHSD17B10
SCHEMBL861300 0.68 KDM4E (0.45) DCPSAPPTLR8DHFRKDM4E
SCHEMBL72801 0.67 DCPS (0.64) DCPSAPPTLR8KDM4EALDH1A1
SCHEMBL29583288 0.67 DCPS (0.64) DCPSAPPTLR8KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C DCPS 1739/4885APP 3508/4885TLR8 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.