SCHEMBL861842

SCHEMBL861842

CC(C)Cc1cc2nc(N)c3ccccc3c2cc1CC(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 8/20 0.45
TLR8 Q9NR97 7/20 0.45
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
HRH2 P25021 1/20 0.38
ADRA1D P25100 1/20 0.38
HTR2A P28223 1/20 0.38
ADORA2A P29274 1/20 0.38
ADRA1A P35348 1/20 0.38
NUDT1 P36639 1/20 0.38
HTR2B P41595 1/20 0.38
PDE4D Q08499 1/20 0.38
KCNH2 Q12809 1/20 0.38
ADK P55263 1/20 0.37
ELANE P08246 1/20 0.37
DCPS Q96C86 1/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
APP P05067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861239 0.78 DCPS (0.36) TLR7TLR8DCPSAPP
SCHEMBL840325 0.73 DHFR (0.49) TLR7TLR8LMNANUDT1DCPS
SCHEMBL5263294 0.72 BACE1 (0.56) TLR7TLR8ADRA1AKCNH2ELANE
SCHEMBL840822 0.71 TLR7 (0.47) TLR7TLR8ADRA1APDE4DKCNH2
SCHEMBL861205 0.68 CYP1A1 (0.50) LMNAPOLBADORA2ADCPSAPP
SCHEMBL861300 0.68 KDM4E (0.45) TLR8ADORA2ADCPSAPP
SCHEMBL72801 0.67 DCPS (0.64) TLR7TLR8LMNAPOLBADORA2A
SCHEMBL29583288 0.67 DCPS (0.64) TLR7TLR8LMNAPOLBADORA2A
SCHEMBL26202926 0.67 TRPM4 (0.42) HTR2AELANE
SCHEMBL8630481 0.67 MDM4 (0.47) LMNAKCNH2DCPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C TLR7 4288/4885TLR8 4706/4885LMNA 3180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.