Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL4148709 | 0.81 | TP53 (0.35) | ADORA3ADORA1ADORA2ADDAH1 | |
| SCHEMBL13056606 | 0.73 | ADORA3 (0.36) | ADORA3ADORA1ADORA2ADDAH1 | |
| SCHEMBL4361446 | 0.68 | TP53 (0.36) | ADORA3ADORA1ADORA2ADDAH1 | |
| SCHEMBL9310219 | 0.68 | ALDH1A1 (0.53) | — | |
| SCHEMBL9125303 | 0.65 | ADORA1 (0.43) | ADORA3ADORA1ADORA2ADDAH1 | |
| SCHEMBL3708487 | 0.65 | ADORA1 (0.43) | ADORA3ADORA1ADORA2ADDAH1 | |
| SCHEMBL829468 | 0.64 | TP53 (0.36) | ADORA3ADORA1ADORA2ADDAH1 | |
| SCHEMBL8901944 | 0.62 | TP53 (0.34) | ADORA3ADORA1ADORA2ADDAH1 | |
| SCHEMBL5201993 | 0.62 | GLA (0.36) | — | |
| SCHEMBL11056691 | 0.61 | GLA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1728898-B1 | Electrolytes for the deposition of gold alloys | ROHM & HAAS ELECT MAT (US) | 2017-02-22 | — | — | EP | disclosed |
| US-8142637-B2 | Gold alloy electrolytes | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2012-03-27 | — | — | US | disclosed |
| US-7465385-B2 | Gold alloy electrolytes | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-12-16 | — | — | US | disclosed |
| US-20060283714-A1 | Gold alloy electrolytes | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2006-12-21 | — | — | US | disclosed |
| EP-1728898-A2 | Electrolytes for the deposition of gold alloys | Rohm and Haas Electronic Materials LLC (US) | 2006-12-06 | — | — | EP | disclosed |