Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632286 | 0.87 | KIT (0.45) | ALDH1A1GAAKMT2AKITKDR | |
| SCHEMBL8632837 | 0.86 | LMNA (0.51) | ALDH1A1POLBGAAKMT2AKIT | |
| SCHEMBL8632208 | 0.84 | STAT3 (0.51) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL8631178 | 0.83 | STAT3 (0.47) | TSHRPOLBKMT2AKITKDR | |
| SCHEMBL8627973 | 0.83 | KDM1A (0.51) | ALDH1A1TSHRPOLBGAAKMT2A | |
| SCHEMBL8634763 | 0.83 | NAT1 (0.45) | ALDH1A1TSHRSMN1; SMN2KMT2AKIT | |
| SCHEMBL8632960 | 0.83 | KEAP1 (0.51) | ALDH1A1TSHRPOLBSMN1; SMN2KMT2A | |
| SCHEMBL8630955 | 0.82 | IMPDH2 (0.54) | GAASMN1; SMN2KITKDRLMNA | |
| SCHEMBL8628949 | 0.82 | ALDH1A1 (0.43) | ALDH1A1POLBGAAHPGDSMN1; SMN2 | |
| SCHEMBL8631402 | 0.81 | MAPT (0.57) | ALDH1A1GAAHPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |