Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | DRD4 | P21917 | 8/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628029 | 0.85 | DRD2 (0.46) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL8628179 | 0.84 | KDM4E (0.50) | DRD2DRD4DRD3SIGMAR1HTR1A | |
| SCHEMBL8629425 | 0.84 | DRD4 (0.56) | DRD2DRD4DRD3HTR1AHTR2C | |
| SCHEMBL8633168 | 0.82 | HTR3A (0.55) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL8628045 | 0.82 | DHFR (0.43) | DRD2DRD4DRD3SIGMAR1HTR1A | |
| SCHEMBL8634968 | 0.82 | DRD4 (0.57) | DRD4ALDH1A1MAPTKMT2APOLB | |
| Hydrochloric Acid SCHEMBL8629946 | 0.81 | DRD4 (0.56) | DRD4ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL8631634 | 0.80 | HRH3 (0.59) | HTR1AHTR2CHTR7ALDH1A1RECQL | |
| SCHEMBL8627836 | 0.78 | DRD4 (0.45) | DRD2DRD4DRD3HTR1AALDH1A1 | |
| SCHEMBL8633681 | 0.78 | RECQL (0.50) | DRD2DRD4DRD3SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780475-A | Antipsychotic indazole derivatives | MERCK, SHARP & DOHME LIMITED (GB) | 1998-07-14 | — | — | US | disclosed |