Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 14/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019441 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL21176648 | 0.99 | ALDH1A1 (0.40) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL4020690 | 0.99 | ALDH1A1 (0.40) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL111712 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL25506725 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL10595694 | 0.84 | CNR2 (0.43) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL2107754 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL30487077 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL4019433 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL31244568 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270168-A1 | SYNTHESIS PROCESS FOR HIGH PURITY ISOSULFAN BLUE USING FLASH CHROMATOGRAPHY IN COMMERCIAL PLANT SCALE | RISING PHARMA HOLDINGS, INC. (US) | 2025-08-28 | — | — | US | claimed |
| EP-3997066-A1 | METHOD FOR THE PREPARATION OF DIARYLMETHANE DYES AND TRIARYLMETHANE DYES INCLUDING ISOSULFAN BLUE | NJ Biopharmaceuticals LLC (US) | 2022-05-18 | — | — | EP | claimed |
| US-7534911-B2 | Process for the preparation of Isosulphan Blue | INNOVASSYNTH TECHNOLOGIES (INDIA) LTD. (IN) | 2009-05-19 | — | — | US | claimed |
| US-20060224003-A1 | A PROCESS FOR THE PREPARATION OF ISOSULPHAN BLUE | RISING PHARMA HOLDINGS, INC. | 2006-10-05 | — | — | US | claimed |
| CN-121850906-A | Preparation method of isothioblue deethylation impurity | 暨明医药科技（苏州）有限公司 | 2026-04-14 | — | — | CN | disclosed |
| US-20250270168-A1 | SYNTHESIS PROCESS FOR HIGH PURITY ISOSULFAN BLUE USING FLASH CHROMATOGRAPHY IN COMMERCIAL PLANT SCALE | RISING PHARMA HOLDINGS, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| US-12180142-B1 | Synthesis process for high purity isosulfan blue using flash chromatography in commercial plant scale | RISING PHARMA HOLDINGS, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| US-20230159444-A1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | PROVEPHARM LIFE SOLUTIONS (FR) | 2023-05-25 | — | — | US | disclosed |
| US-20220289671-A1 | METHOD FOR THE PREPARATION OF DIARYLMETHANE DYES AND TRIARYLMETHANE DYES INCLUDING ISOSULFAN BLUE | NJ BIOPHARMACEUTICALS LLC (US) | 2022-09-15 | — | — | US | disclosed |
| EP-3997066-A1 | METHOD FOR THE PREPARATION OF DIARYLMETHANE DYES AND TRIARYLMETHANE DYES INCLUDING ISOSULFAN BLUE | NJ Biopharmaceuticals LLC (US) | 2022-05-18 | — | — | EP | disclosed |
| WO-2021011440-A1 | METHOD FOR THE PREPARATION OF DIARLYMETHANE DYES AND TRIARYLMETHANE DYES INCLUDING ISOSULFAN BLUE | NJ BIOPHARMACEUTICALS LLC (US) | 2021-01-21 | — | — | WO | disclosed |
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2020-11-05 | — | — | US | disclosed |
| US-7662992-B2 | Process for preparation of isosulfan blue | APICORE, LLC (US) | 2010-02-16 | — | — | US | disclosed |
| US-7534911-B2 | Process for the preparation of Isosulphan Blue | INNOVASSYNTH TECHNOLOGIES (INDIA) LTD. (IN) | 2009-05-19 | — | — | US | disclosed |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-27 | — | — | US | disclosed |
| WO-2008140564-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-13 | — | — | US | disclosed |
| US-20060224003-A1 | A PROCESS FOR THE PREPARATION OF ISOSULPHAN BLUE | RISING PHARMA HOLDINGS, INC. | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, STS, MPST | ALDH1A1 77/4885MEN1 3920/4885HPGD 993/4885 |
| US-20250270168-A1 | SYNTHESIS PROCESS FOR HIGH PURITY ISOSULFAN BLUE USING FLASH CHROMATOGRAPHY IN COMMERCIAL PLANT SCALE | CBS, SLC6A12, RPS4Y1 | ALDH1A1 1717/4885MEN1 2901/4885HPGD 3647/4885 |
| US-20220289671-A1 | METHOD FOR THE PREPARATION OF DIARYLMETHANE DYES AND TRIARYLMETHANE DYES INCLUDING ISOSULFAN BLUE | TST, DDT, CYP2E1 | ALDH1A1 372/4885MEN1 3006/4885HPGD 1074/4885 |
| US-12180142-B1 | Synthesis process for high purity isosulfan blue using flash chromatography in commercial plant scale | CBS, SLC6A12, RPS4Y1 | ALDH1A1 1717/4885MEN1 2901/4885HPGD 3647/4885 |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | SI, STS, MPST | ALDH1A1 70/4885MEN1 3995/4885HPGD 821/4885 |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | ALDH1A1 89/4885MEN1 4175/4885HPGD 982/4885 |
| US-20230159444-A1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | SQOR, SULT1E1, TST | ALDH1A1 445/4885MEN1 914/4885HPGD 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.