Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 14/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244568 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL4019441 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL863081 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL4020690 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL21176648 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL25506725 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL111712 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| Isosulfan Blue Inner Salt SCHEMBL3324345 | 0.74 | MEN1 (0.44) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL10893238 | 0.72 | CNR2 (0.36) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL340854 | 0.71 | MEN1 (0.44) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534911-B2 | Process for the preparation of Isosulphan Blue | INNOVASSYNTH TECHNOLOGIES (INDIA) LTD. (IN) | 2009-05-19 | — | — | US | claimed |
| US-20060224003-A1 | A PROCESS FOR THE PREPARATION OF ISOSULPHAN BLUE | RISING PHARMA HOLDINGS, INC. | 2006-10-05 | — | — | US | claimed |
| US-20250270168-A1 | SYNTHESIS PROCESS FOR HIGH PURITY ISOSULFAN BLUE USING FLASH CHROMATOGRAPHY IN COMMERCIAL PLANT SCALE | RISING PHARMA HOLDINGS, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| US-12180142-B1 | Synthesis process for high purity isosulfan blue using flash chromatography in commercial plant scale | RISING PHARMA HOLDINGS, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| US-10723745-B2 | Isosulfan blue, its crystalline form and process for preparation thereof | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-07-28 | — | — | US | disclosed |
| US-20190225626-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2019-07-25 | — | — | US | disclosed |
| US-7534911-B2 | Process for the preparation of Isosulphan Blue | INNOVASSYNTH TECHNOLOGIES (INDIA) LTD. (IN) | 2009-05-19 | — | — | US | disclosed |
| US-20060224003-A1 | A PROCESS FOR THE PREPARATION OF ISOSULPHAN BLUE | RISING PHARMA HOLDINGS, INC. | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225626-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | SI, IK, RPS4Y1 | PPARG 4787/4885ALDH1A1 809/4885MEN1 2280/4885 |
| US-20250270168-A1 | SYNTHESIS PROCESS FOR HIGH PURITY ISOSULFAN BLUE USING FLASH CHROMATOGRAPHY IN COMMERCIAL PLANT SCALE | CBS, SLC6A12, RPS4Y1 | PPARG 4562/4885ALDH1A1 1717/4885MEN1 2901/4885 |
| US-12180142-B1 | Synthesis process for high purity isosulfan blue using flash chromatography in commercial plant scale | CBS, SLC6A12, RPS4Y1 | PPARG 4562/4885ALDH1A1 1717/4885MEN1 2901/4885 |
| US-10723745-B2 | Isosulfan blue, its crystalline form and process for preparation thereof | SI, IK, RPS4Y1 | PPARG 4787/4885ALDH1A1 809/4885MEN1 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.