Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635192 | 0.87 | RXRA (0.35) | KCNJ6KCNJ3LTC4SGPBAR1 | |
| SCHEMBL8635629 | 0.85 | FLT1 (0.36) | KCNJ6KCNJ3LTC4S | |
| SCHEMBL8635329 | 0.84 | SLC9A1 (0.35) | — | |
| SCHEMBL8635012 | 0.84 | NSD2 (0.36) | — | |
| SCHEMBL7766601 | 0.84 | SLC9A1 (0.56) | — | |
| SCHEMBL8634267 | 0.82 | KEAP1 (0.41) | KCNJ6KCNJ3 | |
| SCHEMBL8633950 | 0.81 | SIRT2 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL8632865 | 0.81 | RORC (0.36) | GPBAR1 | |
| SCHEMBL8634338 | 0.79 | ALDH1A1 (0.38) | KCNJ6KCNJ3GPBAR1 | |
| SCHEMBL8638285 | 0.78 | PDE4B (0.41) | LTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |