Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635629 | 0.88 | FLT1 (0.36) | POLBTDP1RXRARXRBRXRG | |
| SCHEMBL8634362 | 0.88 | NSD2 (0.40) | NSD2ESR1POLBAPEX1RECQL | |
| SCHEMBL8638285 | 0.88 | PDE4B (0.41) | MAPT | |
| SCHEMBL8635192 | 0.87 | RXRA (0.35) | L3MBTL1RXRARXRBRXRGSLC9A1 | |
| SCHEMBL8635329 | 0.87 | SLC9A1 (0.35) | L3MBTL1RXRARXRBRXRGSLC9A1 | |
| SCHEMBL8634338 | 0.87 | ALDH1A1 (0.38) | POLBSLC9A1MAPT | |
| SCHEMBL8634555 | 0.86 | MKNK1 (0.38) | RECQLL3MBTL1GAA | |
| SCHEMBL8634267 | 0.85 | KEAP1 (0.41) | RXRARXRBRXRG | |
| SCHEMBL8635203 | 0.85 | HSP90AA1 (0.35) | NSD2ESR1POLBAPEX1RECQL | |
| SCHEMBL8633203 | 0.85 | MEN1 (0.35) | ESR1POLBSLC9A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |