Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | CBR1 | P16152 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438989 | 0.86 | MAPT (0.62) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL8502158 | 0.79 | FFAR1 (0.56) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL16705542 | 0.79 | HTR2A (0.55) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL10672137 | 0.79 | SLC6A2 (0.52) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL554810 | 0.79 | MAOA (0.61) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL3469104 | 0.79 | TTR (0.61) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL2092929 | 0.79 | FFAR1 (0.53) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL2087304 | 0.79 | CYP1A2 (0.67) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL28345487 | 0.78 | TTR (0.59) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL7186092 | 0.77 | TTR (0.75) | TTRMAPTHPGDNR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-209854032-U | Production system of 4- (2, 4-dichlorophenoxy) sodium phenolbutyrate | 辽宁先达农业科学有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-209854032-U | Production system of 4- (2, 4-dichlorophenoxy) sodium phenolbutyrate | 辽宁先达农业科学有限公司 | 2019-12-27 | — | — | CN | disclosed |
| US-5712226-A | Optically active D-pyridyloxy phenoxy propionate herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-27 | — | — | US | disclosed |
| US-5254527-A | Optically active herbicidal ethyl-2-(4-(6-chloro-benzoxazol-2-yloxy)-phenoxy)-propionate | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |
| US-4948420-A | Herbicidal aryloxy phenoxy acyl malonates | BUDAPESTI VEGYIMUVEK (HU) | 1990-08-14 | — | — | US | disclosed |
| US-4765825-A | PARTICULARLY EFFECTIVE AS PREEMERGENCE HERBICIDES FOR GRASSES | BUDAPESTI VEGYIMUVEK (HU) | 1988-08-23 | — | — | US | disclosed |
| US-4531969-A | Combatting growth of weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0002800-B1 | Optically active alpha-phenoxypropionic acid dervatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-02 | — | — | EP | disclosed |
| EP-0002800-A1 | Optically active alpha-phenoxypropionic acid dervatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |