Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13274466 | 0.78 | SMN1; SMN2 (0.34) | ALDH1A1TSHRNPSR1 | |
| SCHEMBL18865608 | 0.76 | ADORA3 (0.30) | — | |
| SCHEMBL19209829 | 0.76 | ALPL (0.31) | — | |
| SCHEMBL11967294 | 0.76 | — | — | |
| SCHEMBL22795798 | 0.75 | NOS3 (0.32) | — | |
| SCHEMBL23204371 | 0.73 | BRD4 (0.37) | ALDH1A1 | |
| SCHEMBL25150908 | 0.73 | — | — | |
| SCHEMBL13180352 | 0.73 | SMN1; SMN2 (0.39) | ALDH1A1TSHR | |
| SCHEMBL18659476 | 0.73 | NOS3 (0.33) | — | |
| SCHEMBL23234037 | 0.72 | PTGS2 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742168-B2 | Process for the production of acetic acid | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2014-06-03 | — | — | US | claimed |
| US-8637699-B2 | Process for the manufacture of acetic acid | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2014-01-28 | — | — | US | claimed |
| US-20120310009-A1 | Process for the Production of Acetic Acid | LYONDELL CHEMICAL COMPANY (US) | 2012-12-06 | — | — | US | claimed |
| US-20120264971-A1 | PROCESS FOR THE MANUFACTURE OF ACETIC ACID | LYONDELLBASELL ACETYLS, LLC | 2012-10-18 | — | — | US | claimed |
| US-20240067629-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2024-02-29 | — | — | US | disclosed |
| US-11753399-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO INC. (KR) | 2023-06-15 | — | — | US | disclosed |
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO INC. (KR) | 2023-06-15 | — | — | US | disclosed |
| WO-2023083285-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-12 | — | — | US | disclosed |
| US-11548883-B2 | Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same | LEGOCHEM BIOSCIENCES, INC. (KR) | 2023-01-10 | — | — | US | disclosed |
| US-20120135980-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION | 2012-05-31 | — | — | US | disclosed |
| US-20120129846-A1 | GAMMA SECRETASE MODULATORS | Merck, Sharp & Dohme, Corp. | 2012-05-24 | — | — | US | disclosed |
| US-20110306593-A1 | GAMMA SECRETASE MODULATORS | MERCK SHARP & DOHME LLC | 2011-12-15 | — | — | US | disclosed |
| US-20110294784-A1 | GAMMA SECRETASE MODULATORS | MERCK SHARP & DOHME LLC | 2011-12-01 | — | — | US | disclosed |
| US-20100234364-A1 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. | 2010-09-16 | — | — | US | disclosed |
| WO-2008106202-A1 | THERAMUTEIN MODULATORS | HOUSEY GERARD M (US) | 2008-09-04 | — | — | WO | disclosed |
| US-7342016-B2 | Farnesyl protein transferase inhibitors as antitumor agents | SCHERING CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-7279474-B2 | Substituted pyrrolo[2,3-d]pyrimidines as antagonists of the corticotropin releasing factor (CRF) | GLAXO GROUP LIMITED (GB) | 2007-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264971-A1 | PROCESS FOR THE MANUFACTURE OF ACETIC ACID | DBI, IDH1, ACAD9 | ALDH1A1 69/4885TSHR 1854/4885NPSR1 4866/4885 |
| US-11548883-B2 | Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same | ENPP2, PLA2G10, LPCAT1 | ALDH1A1 4207/4885TSHR 3471/4885NPSR1 1809/4885 |
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | TTK, TTBK1, TTBK2 | ALDH1A1 3055/4885TSHR 2992/4885NPSR1 3834/4885 |
| US-20110294784-A1 | GAMMA SECRETASE MODULATORS | BACE1, BACE2, GSAP | ALDH1A1 2161/4885TSHR 4429/4885NPSR1 1332/4885 |
| US-20120135980-A1 | GAMMA SECRETASE MODULATORS | BACE1, BACE2, GSAP | ALDH1A1 2161/4885TSHR 4429/4885NPSR1 1332/4885 |
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR77 | ALDH1A1 3516/4885TSHR 4738/4885NPSR1 4536/4885 |
| US-20120129846-A1 | GAMMA SECRETASE MODULATORS | BACE1, BACE2, PSEN1 | ALDH1A1 3689/4885TSHR 4173/4885NPSR1 1530/4885 |
| US-20120310009-A1 | Process for the Production of Acetic Acid | DBI, FLI1, ACADM | ALDH1A1 52/4885TSHR 1979/4885NPSR1 4854/4885 |
| US-20110306593-A1 | GAMMA SECRETASE MODULATORS | BACE1, BACE2, PSEN1 | ALDH1A1 3613/4885TSHR 4402/4885NPSR1 1402/4885 |
| US-20240067629-A1 | THERAPEUTIC COMPOUNDS | NPC1, CCR5, FURIN | ALDH1A1 742/4885TSHR 4855/4885NPSR1 1925/4885 |
| US-20100234364-A1 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CCR2, CCR9, CCR1 | ALDH1A1 1572/4885TSHR 1538/4885NPSR1 739/4885 |
| US-11753399-B2 | Therapeutic compounds | NPC1, CCR5, FURIN | ALDH1A1 742/4885TSHR 4855/4885NPSR1 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.