Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780796 | 0.97 | KDM4E (0.41) | MAOBHTR2AHTR2CMAPTKDM4E | |
| SCHEMBL8780841 | 0.86 | ALDH1A1 (0.43) | MAOBHTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL8780758 | 0.85 | LMNA (0.56) | MAOBMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8780875 | 0.80 | ALDH1A1 (0.45) | MAOBHTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL8780829 | 0.80 | RIPK2 (0.43) | MAOBMAPTKDM4ETSHRMCHR1 | |
| SCHEMBL8780993 | 0.79 | THRA (0.40) | MAOBHTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL8780837 | 0.77 | L3MBTL1 (0.45) | MAOBLMNAMCHR1 | |
| SCHEMBL8780779 | 0.77 | KCNH2 (0.51) | MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL8780768 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNASMN1; SMN2BRD4 | |
| SCHEMBL8780919 | 0.74 | HRH3 (0.41) | MAOBKDM4EMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |