Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780841 | 0.90 | ALDH1A1 (0.43) | LMNAKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL8780796 | 0.88 | KDM4E (0.41) | LMNAKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8780783 | 0.85 | HTR1D (0.41) | LMNAKDM4EALDH1A1L3MBTL1MCHR1 | |
| SCHEMBL8780811 | 0.85 | MAOB (0.41) | LMNAKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8780875 | 0.83 | ALDH1A1 (0.45) | LMNAKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL8780837 | 0.83 | L3MBTL1 (0.45) | LMNAL3MBTL1MCHR1MAOB | |
| SCHEMBL8780993 | 0.82 | THRA (0.40) | LMNAKDM4EALDH1A1MCHR1MAOB | |
| SCHEMBL8780798 | 0.80 | BCHE (0.50) | LMNAKDM4EMAPTL3MBTL1MCHR1 | |
| SCHEMBL8780892 | 0.79 | RXFP1 (0.42) | MAPTMCHR1 | |
| SCHEMBL8780768 | 0.78 | ALDH1A1 (0.38) | LMNAKDM4EALDH1A1SMN1; SMN2BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |