Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938661 | 0.95 | ALDH1A1 (0.47) | ALDH1A1CA4KDM4ELMNAMAPT | |
| SCHEMBL149815 | 0.93 | ALDH1A1 (0.48) | ALDH1A1CA4KDM4ELMNAMAPT | |
| Water SCHEMBL28741257 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CA4KDM4ELMNAMAPT | |
| Water SCHEMBL7558083 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CA4KDM4ELMNAMAPT | |
| Potassium Ion SCHEMBL12980475 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CA4KDM4ELMNAMAPT | |
| SCHEMBL27748681 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CA4KDM4ELMNAMAPT | |
| Potassium Ion SCHEMBL1389321 | 0.90 | ALDH1A1 (0.48) | ALDH1A1CA4KDM4ELMNAMAPT | |
| Potassium Chloride SCHEMBL27337973 | 0.89 | ALDH1A1 (0.44) | ALDH1A1CA4KDM4ELMNAMAPT | |
| Water SCHEMBL17843652 | 0.89 | ALDH1A1 (0.47) | ALDH1A1CA4KDM4ELMNAMAPT | |
| SCHEMBL4617845 | 0.87 | ALDH1A1 (0.48) | ALDH1A1CA4KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106413739-B | NBP158 and uses thereof | 张文涛 | 2019-09-17 | — | — | CN | disclosed |
| CN-110114074-A | For treating or preventing the coagulation factor substitute products of bleeding | 德国杰特贝林生物制品有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-109789205-A | Anti- PD-1(CD279) antibody | 艾伯维生物制药股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109562189-A | anti-cMet antibody drug conjugates and methods of use thereof | 艾伯维生物制药股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109476750-A | anti-CD 40 antibodies and uses thereof | 艾伯维生物制药股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109310738-A | Composition and method for treating cancer | 克罗米科股份有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-107849142-A | Antagonistic anti-tumor necrosis factor receptor superfamily antibodies | 综合医院公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-106659770-A | Pharmaceutical compositions | 葛兰素史密斯克莱有限责任公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106456809-A | Antibodies targeting b-cell receptor complex membrane bound igm and uses thereof | 韦尔特生物分子医药有限责任公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106413739-A | NBP158 and uses thereof | 张文涛 | 2017-02-15 | — | — | CN | disclosed |
| CN-1147589-C | Method for detecting flu A-type and B-type in clinic sample | �����������ҽѧ�о������ | 2004-04-28 | — | — | CN | disclosed |
| CN-1433324-A | Interferon gamma conjugates | MAXYGEN APS (US) | 2003-07-30 | — | — | CN | disclosed |
| CN-1404401-A | G-CSF conjugates | MAXYGEN APS (US) | 2003-03-19 | — | — | CN | disclosed |
| CN-1400910-A | Coagulation factor VII or VIIa-like molecules | MAXYGEN A P S (DK) | 2003-03-05 | — | — | CN | disclosed |
| CN-1091447-C | 4, 7-dialkoxy N-acetylneuraminic acid derivatives and methods for their use in clinical samples for the detection of influenza type A and B viruses | OKLAHOMA MEDICAL RESAERCH FOUN (US) | 2002-09-25 | — | — | CN | disclosed |
| CN-1324954-A | Method for detecting flu A-type and B-type in clinic sample | OKLAHOMA STATE MEDICAL RES FOU (US) | 2001-12-05 | — | — | CN | disclosed |
| CN-1300221-A | Treatment of cardiao hypertrophy | GENENTECH INC (US) | 2001-06-20 | — | — | CN | disclosed |
| CN-1245434-A | Stable liquid interferon formulations | BIOGEN INC (US) | 2000-02-23 | — | — | CN | disclosed |
| CN-1205011-A | 4, 7-dialkoxy N-acetylneuraminic acid derivatives and methods for their use in clinical samples for the detection of influenza type A and B viruses | OKLAHOMA MED RES FOUND (US) | 1999-01-13 | — | — | CN | disclosed |
| US-5653917-A | Rust-removing alkali metal hydrogen citrate composition | SINGERMAN GARY M (US) | 1997-08-05 | — | — | US | disclosed |