Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TK2 | O00142 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497191 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL25504633 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL25505398 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL19224119 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL14063727 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL25505352 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL12453196 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL12352406 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL12149468 | 1.00 | TK1 (0.69) | TK1POLBTK2 | |
| SCHEMBL655193 | 0.91 | TK1 (0.67) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| US-20240067673-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | BGI SHENZHEN (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | ILLUMINA, INC. | 2023-10-19 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | Nuclera Nucleics Ltd. (GB) | 2023-06-08 | — | — | US | disclosed |
| US-20230148152-A1 | METHOD OF SYNTHESIZING SINGLE-STRANDED NUCLEOTIDE SEQUENCE, BLOCKED NUCLEOSIDE TRIPHOSPHATES AND RELATED METHODS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-05-11 | — | — | US | disclosed |
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| US-8361727-B2 | 3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110287427-A1 | 3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-8030466-B2 | 3′-o-fluorescently modified nucleotides and uses thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-10-04 | — | — | US | disclosed |
| US-20110076679-A1 | 3'-O-FLUORESCENTLY MODIFIED NUCLEOTIDES AND USES THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-03-31 | — | — | US | disclosed |
| US-7906639-B2 | Oligonucleotides having a 2′-O,4′-C-ethylene nucleotide in the third position of the 3′-end | SANKYO COMPANY, LIMITED (JP) | 2011-03-15 | — | — | US | disclosed |
| US-20090305278-A1 | SEQUENCE DETERMINATION IN CONFINED REGIONS | Life Technologies Corporation (US) | 2009-12-10 | — | — | US | disclosed |
| US-7507859-B2 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC (US) | 2009-03-24 | — | — | US | disclosed |
| EP-1688493-B1 | METHOD OF DETECTING GENETIC POLYMORPHISM | DAIICHI SANKYO CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7276598-B2 | Phosphorylation reagents for improved processes to convert terminal hydroxyl groups of oligonucleotides into phosphate monoesters | SIGMA-ALDRICH CO. (US) | 2007-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | TK1 166/4885POLB 76/4885TK2 255/4885 |
| US-20110076679-A1 | 3'-O-FLUORESCENTLY MODIFIED NUCLEOTIDES AND USES THEREOF | NUDT1, RNGTT, DNTT | TK1 89/4885POLB 23/4885TK2 154/4885 |
| US-20240229026-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | TK1 701/4885POLB 56/4885TK2 844/4885 |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, ALKBH1 | TK1 271/4885POLB 190/4885TK2 372/4885 |
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | NT5C3B, NSUN2, DUT | TK1 132/4885POLB 42/4885TK2 167/4885 |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | TK1 8/4885POLB 108/4885TK2 27/4885 |
| US-11643657-B2 | Chiral control | RNGTT, POLI, NSUN3 | TK1 701/4885POLB 56/4885TK2 844/4885 |
| US-20240067673-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | NT5C3B, NT5E, NT5C2 | TK1 67/4885POLB 94/4885TK2 72/4885 |
| US-20230148152-A1 | METHOD OF SYNTHESIZING SINGLE-STRANDED NUCLEOTIDE SEQUENCE, BLOCKED NUCLEOSIDE TRIPHOSPHATES AND RELATED METHODS | RNGTT, NT5C3B, TYMP | TK1 58/4885POLB 4/4885TK2 92/4885 |
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | RNGTT, POLM, POLRMT | TK1 259/4885POLB 5/4885TK2 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.