Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 6/20 | 0.42 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375905 | 0.79 | LMNA (0.47) | ALDH1A1LMNAMETTL3CLCN2CLIC1 | |
| SCHEMBL8903199 | 0.76 | NLRP3 (0.40) | ALDH1A1CXCL8PTGS2AKR1B10ABCB11 | |
| Hydrochloric Acid SCHEMBL15110990 | 0.68 | LMNA (0.49) | ALDH1A1LMNAMETTL3CLCN2CLIC1 | |
| SCHEMBL8130619 | 0.68 | ALDH1A1 (0.67) | ALDH1A1LMNAMETTL3CLCN2CLIC1 | |
| SCHEMBL9771551 | 0.67 | MAPT (0.41) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL9771534 | 0.67 | CYP3A4 (0.31) | MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL30499673 | 0.67 | ALDH1A1 (0.65) | ALDH1A1LMNAMETTL3CLCN2CLIC1 | |
| SCHEMBL7760768 | 0.67 | ALDH1A1 (0.65) | ALDH1A1LMNAMETTL3CLCN2CLIC1 | |
| SCHEMBL11345544 | 0.65 | CLCN2 (0.50) | ALDH1A1LMNAMETTL3CLCN2CLIC1 | |
| SCHEMBL7162249 | 0.64 | PTGS2 (0.58) | ALDH1A1LMNAMETTL3CLCN2CLIC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2598540-B2 | — | — | 1997-04-09 | — | — | JP | claimed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | claimed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | claimed |