Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903164 | 0.79 | ALDH1A1 (0.51) | LMNAALDH1A1PTGS2MEN1MAPK1 | |
| SCHEMBL8945494 | 0.73 | ADRA2A (0.39) | LMNAMEN1KMT2ACYP1A2GAA | |
| Hydrochloric Acid SCHEMBL15110990 | 0.72 | LMNA (0.49) | LMNAALDH1A1PTGS2MEN1MAPK1 | |
| SCHEMBL8130619 | 0.68 | ALDH1A1 (0.67) | LMNAALDH1A1PTGS2MEN1MAPK1 | |
| SCHEMBL7162249 | 0.68 | PTGS2 (0.58) | LMNAALDH1A1PTGS2MEN1MAPK1 | |
| SCHEMBL30499673 | 0.67 | ALDH1A1 (0.65) | LMNAALDH1A1PTGS2MEN1MAPK1 | |
| SCHEMBL7760768 | 0.67 | ALDH1A1 (0.65) | LMNAALDH1A1PTGS2MEN1MAPK1 | |
| SCHEMBL2760397 | 0.67 | PTGS2 (0.65) | LMNAPTGS2MEN1MAPK1KMT2A | |
| SCHEMBL180306 | 0.66 | CYP3A4 (0.46) | LMNAALDH1A1PTGS2MEN1MAPK1 | |
| SCHEMBL29370015 | 0.66 | CYP3A4 (0.46) | LMNAALDH1A1PTGS2MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003096-A | Alkylsilylaniline intermediates for herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-26 | — | — | US | claimed |
| US-4910306-A | Combining a sulfonyl halide with N-trialkylsilylaniline | THE DOW CHEMICAL COMPANY (US) | 1990-03-20 | — | — | US | claimed |
| EP-0340828-B1 | 5-Fluoromethyl-1,2,4-triazolo(1,5-a)-pyrimidine-2-sulfonamides, process for their preparation and compositions for their use as herbicides | DOWELANCO (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5003096-A | Alkylsilylaniline intermediates for herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-5003096-A | Alkylsilylaniline intermediates for herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4959473-A | 7-ethoxy-5-fluoromethyl-1,2,4-triazole[1,5-a]-pyrimidine-2-sulfonamindes | THE DOW CHEMICAL COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| US-4910306-A | Combining a sulfonyl halide with N-trialkylsilylaniline | THE DOW CHEMICAL COMPANY (US) | 1990-03-20 | — | — | US | disclosed |
| US-4910306-A | Combining a sulfonyl halide with N-trialkylsilylaniline | THE DOW CHEMICAL COMPANY (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0340828-A1 | 5-Fluoromethyl-1,2,4-triazolo(1,5-a)-pyrimidine-2-sulfonamides, process for their preparation and compositions for their use as herbicides | DowElanco (US) | 1989-11-08 | — | — | EP | disclosed |
| WO-1989010368-A1 | 5-FLUOROMETHYL-1,2,4-TRIAZOLO[1,5-a]-PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS FOR THEIR USE AS HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1989-11-02 | — | — | WO | disclosed |