SCHEMBL891105

SCHEMBL891105

CCn1c(C)cc(C)c1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 3/20 0.44
GPR35 Q9HC97 1/20 0.39
NOTUM Q6P988 2/20 0.38
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 3/20 0.35
USP2 O75604 2/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
NR4A1 P22736 1/20 0.34
APEX1 P27695 1/20 0.34
APOBEC3A P31941 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9897985 0.81 POLB (0.42) KDM4ELMNAPOLBGPR35NOTUM
SCHEMBL7253530 0.78 KMT2A (0.37) KDM4EPOLBGPR35KMT2AMEN1
SCHEMBL27210056 0.78 CYP1A2 (0.46) KDM4ELMNANOTUMKMT2AMEN1
SCHEMBL257495 0.73 FNTA (0.45) KDM4ELMNAPOLBKMT2AMEN1
SCHEMBL12397750 0.73 HSD17B10 (0.46) KDM4ELMNAPOLBKMT2AALDH1A1
SCHEMBL9955427 0.72 NR4A1 (0.39) KDM4EGPR35NOTUMKMT2AMEN1
SCHEMBL12926004 0.69 KDM4E (0.48) KDM4ELMNAPOLBKMT2AMEN1
SCHEMBL9134415 0.68 KDM4E (0.46) KDM4ELMNAPOLBGPR35NOTUM
SCHEMBL4957913 0.68 GPR35 (0.50) KDM4EPOLBGPR35NOTUMKMT2A
SCHEMBL29712815 0.68 ALDH1A1 (0.34) KDM4ELMNAPOLBGPR35NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1716089-B1 METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL CO (US) 2015-04-08 EP claimed
US-7384886-B2 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-06-10 US claimed
US-5986153-A DECOLORING A SOLUTION OF PYRROLES MIXED WITH OLEFINS USING ALUMINUM, ZIRCONIUM AND BORATE PHILLIPS PETROLEUM COMPANY (US) 1999-11-16 US claimed
US-5399539-A Chromium, pyrrole and aluminum compounds on supports, recovering and activation PHILLIPS PETROLEUM COMPANY (US) 1995-03-21 US claimed
US-12637399-B2 Flexible production of benzene and derivatives thereof via oligomerization of ethylene CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-05-26 US disclosed
US-12618016-B2 Methods for producing aviation fuels CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-05-05 US disclosed
US-20260103649-A1 SUSTAINABLE AVIATION FUEL FROM NORMAL ALPHA OLEFIN BYPRODUCTS AND PROCESS FOR SAME CHEVRON PHILLIPS CHEMICAL CO LP (US) 2026-04-16 US disclosed
WO-2026043730-A1 METHODS FOR PRODUCING AVIATION FUELS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-02-26 WO disclosed
US-20260049256-A1 METHODS FOR PRODUCING AVIATION FUELS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2026-02-19 US disclosed
US-12540287-B2 Sustainable aviation fuel from normal alpha olefin byproducts and process for same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-02-03 US disclosed
US-12528999-B2 Sustainable jet fuel and process CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-01-20 US disclosed
US-20250162963-A1 ETHYLENE TRIMERIZATION CATALYST SYSTEMS CONTAINING AROMATIC SOLVENTS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2025-05-22 US disclosed
US-5393719-A Chromium oxide on inorganic oxide support, pyrrole compound, non-hydrolyzed metal alkyl; produces comonomer in situ for low density polymers with short chain branching PHILLIPS PETROLEUM COMPANY (US) 1995-02-28 US disclosed
US-5382738-A Pyrrole-chromium complexes for oligomerization of olefins PHILLIPS PETROLEUM COMPANY (US) 1995-01-17 US disclosed
US-5376612-A Selective catalysts for trimerization, oligomerization or polymerization of olefins PHILLIPS PETROLEUM COMPANY (US) 1994-12-27 US disclosed
US-5360879-A From waste chromium compound, alkyl aluminum, oxide support, olefins PHILLIPS PETROLEUM COMPANY (US) 1994-11-01 US disclosed
US-5340785-A Coordination catalyst PHILLIPS PETROLEUM COMPANY (US) 1994-08-23 US disclosed
EP-0608447-A1 Process for the preparation of a catalyst for olefin polymerization PHILLIPS PETROLEUM COMPANY (US) 1994-08-03 EP disclosed
US-5331070-A Polyethylene with short chain branching, chromium oxide, pyrrole, triethylaluminum catalyst PHILLIPS PETROLEUM COMPANY (US) 1994-07-19 US disclosed
EP-0548805-A1 Process for the preparation of polymerisation catalysts PHILLIPS PETROLEUM COMPANY (US) 1993-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618016-B2 Methods for producing aviation fuels CYP4F8, CYP8B1, CYP2E1 KDM4E 2212/4885LMNA 2353/4885POLB 590/4885
US-20250162963-A1 ETHYLENE TRIMERIZATION CATALYST SYSTEMS CONTAINING AROMATIC SOLVENTS NOD2, EXOC4, AHR KDM4E 1524/4885LMNA 3421/4885POLB 1866/4885
US-12637399-B2 Flexible production of benzene and derivatives thereof via oligomerization of ethylene CYP2E1, ACHE, CYP1A1 KDM4E 3345/4885LMNA 2471/4885POLB 1391/4885
US-20260103649-A1 SUSTAINABLE AVIATION FUEL FROM NORMAL ALPHA OLEFIN BYPRODUCTS AND PROCESS FOR SAME YAP1, CYP4F8, SCD KDM4E 3851/4885LMNA 2968/4885POLB 2610/4885
US-12528999-B2 Sustainable jet fuel and process CYP2E1, ADH1C, PCCA KDM4E 3720/4885LMNA 2064/4885POLB 732/4885
US-20260049256-A1 METHODS FOR PRODUCING AVIATION FUELS CYP4F8, CPT1A, CBR1 KDM4E 2517/4885LMNA 2879/4885POLB 526/4885
US-12540287-B2 Sustainable aviation fuel from normal alpha olefin byproducts and process for same ADH1A, ADH1C, YAP1 KDM4E 3970/4885LMNA 2460/4885POLB 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.