Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918176 | 0.86 | CCR3 (0.36) | MEN1KMT2A | |
| SCHEMBL8918039 | 0.85 | HSD17B1 (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL8917789 | 0.84 | HTR6 (0.38) | ALDH1A1TSHRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8916300 | 0.84 | MEN1 (0.39) | GAAL3MBTL1SMN1; SMN2HTR6MEN1 | |
| SCHEMBL8917165 | 0.83 | CYP1A2 (0.31) | LMNA | |
| SCHEMBL8917402 | 0.81 | SLC40A1 (0.40) | MMP2MMP3MEN1KMT2A | |
| SCHEMBL8917377 | 0.80 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HTR6KMT2A | |
| SCHEMBL8920824 | 0.75 | SLC40A1 (0.37) | GAAALDH1A1POLB | |
| SCHEMBL8917762 | 0.75 | KAT6A (0.38) | GAAHPGDALDH1A1L3MBTL1HTR6 | |
| SCHEMBL8916155 | 0.74 | HTR6 (0.36) | HPGDALDH1A1TSHRL3MBTL1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |