Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920824 | 0.77 | SLC40A1 (0.37) | POLBHTTALDH1A1GAA | |
| SCHEMBL8918176 | 0.74 | CCR3 (0.36) | MEN1HTTKMT2ACYP1A2 | |
| SCHEMBL8917696 | 0.74 | GAA (0.39) | HPGDPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL8918039 | 0.74 | HSD17B1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8917377 | 0.73 | ALDH1A1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL8916155 | 0.73 | HTR6 (0.36) | HPGDPOLBMEN1MAPTHTT | |
| SCHEMBL8919657 | 0.73 | PTGS2 (0.41) | PTGS1PTGS2 | |
| SCHEMBL8916300 | 0.71 | MEN1 (0.39) | POLBMEN1MAPTKMT2AGAA | |
| SCHEMBL8917789 | 0.71 | HTR6 (0.38) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL8917402 | 0.70 | SLC40A1 (0.40) | MEN1KMT2AMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |