Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | IL1RN | P18510 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916155 | 0.85 | HTR6 (0.36) | SLC40A1POLBALDH1A1HTT | |
| SCHEMBL8917377 | 0.85 | ALDH1A1 (0.36) | NPSR1RXFP1ALDH1A1EDNRBEDNRA | |
| SCHEMBL8918176 | 0.80 | CCR3 (0.36) | SLC40A1HTTEGFRERBB2 | |
| SCHEMBL8918039 | 0.77 | HSD17B1 (0.35) | SLC40A1ALDH1A1ERAP1 | |
| SCHEMBL8918357 | 0.77 | HPGD (0.37) | POLBALDH1A1GAAHTT | |
| SCHEMBL8917696 | 0.75 | GAA (0.39) | POLBALDH1A1GAA | |
| SCHEMBL8916300 | 0.74 | MEN1 (0.39) | SLC40A1POLBGAAEGFRERBB2 | |
| SCHEMBL8917789 | 0.74 | HTR6 (0.38) | ALDH1A1KEAP1 | |
| SCHEMBL8688502 | 0.74 | NPSR1 (0.35) | SLC40A1NPSR1RXFP1POLBGAA | |
| SCHEMBL8917402 | 0.73 | SLC40A1 (0.40) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |