Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918176 | 0.83 | CCR3 (0.36) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8917696 | 0.83 | GAA (0.39) | LMNA | |
| SCHEMBL8918039 | 0.83 | HSD17B1 (0.35) | CYP2C9 | |
| SCHEMBL8916300 | 0.82 | MEN1 (0.39) | — | |
| SCHEMBL8917789 | 0.82 | HTR6 (0.38) | LMNA | |
| SCHEMBL8918871 | 0.80 | — | — | |
| SCHEMBL8917402 | 0.78 | SLC40A1 (0.40) | — | |
| SCHEMBL8918771 | 0.76 | PTGS2 (0.35) | CYP2C9 | |
| SCHEMBL8920824 | 0.73 | SLC40A1 (0.37) | HTT | |
| SCHEMBL8917762 | 0.73 | KAT6A (0.38) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |