Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916300 | 0.88 | MEN1 (0.39) | SLC40A1MEN1KMT2A | |
| SCHEMBL8918176 | 0.83 | CCR3 (0.36) | SLC40A1MEN1KMT2APTGDR2 | |
| SCHEMBL8918039 | 0.83 | HSD17B1 (0.35) | SLC40A1MEN1KMT2A | |
| SCHEMBL8917696 | 0.81 | GAA (0.39) | MEN1KMT2AMMP3MMP2 | |
| SCHEMBL8917789 | 0.80 | HTR6 (0.38) | MEN1KMT2A | |
| SCHEMBL8917165 | 0.78 | CYP1A2 (0.31) | — | |
| SCHEMBL8917343 | 0.74 | PTGS2 (0.41) | — | |
| SCHEMBL8920824 | 0.73 | SLC40A1 (0.37) | SLC40A1 | |
| SCHEMBL8917762 | 0.73 | KAT6A (0.38) | SLC40A1KAT6AMEN1KMT2A | |
| SCHEMBL8916155 | 0.72 | HTR6 (0.36) | SLC40A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |