Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918176 | 0.85 | CCR3 (0.36) | MEN1KMT2A | |
| SCHEMBL8917696 | 0.84 | GAA (0.39) | HTR6ALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL8918039 | 0.84 | HSD17B1 (0.35) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8916300 | 0.84 | MEN1 (0.39) | HTR6KEAP1NFE2L2MAPTSMN1; SMN2 | |
| SCHEMBL8917165 | 0.82 | CYP1A2 (0.31) | LMNA | |
| SCHEMBL8917402 | 0.80 | SLC40A1 (0.40) | MEN1KMT2A | |
| SCHEMBL8920824 | 0.74 | SLC40A1 (0.37) | ALDH1A1KEAP1 | |
| SCHEMBL8921429 | 0.74 | PTGS2 (0.42) | NSD2 | |
| SCHEMBL8916155 | 0.73 | HTR6 (0.36) | HTR6ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL8917377 | 0.73 | ALDH1A1 (0.36) | HTR6ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |