Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921166 | 0.89 | CA2 (0.33) | SCN9AFBP1NLRP3CA2SLC40A1 | |
| SCHEMBL8917749 | 0.88 | FBP1 (0.32) | FBP1CA2 | |
| SCHEMBL8917277 | 0.84 | TRPV4 (0.34) | FBP1ALDH1A1 | |
| SCHEMBL8918872 | 0.84 | KDM1A (0.45) | S1PR1KDM1AHTR6CA2SLC40A1 | |
| SCHEMBL8918537 | 0.75 | FBP1 (0.33) | FBP1ALDH1A1 | |
| SCHEMBL8919620 | 0.74 | MAPT (0.34) | — | |
| SCHEMBL8916660 | 0.73 | SGK1 (0.33) | CNR1CNR2 | |
| SCHEMBL8916271 | 0.72 | CA1 (0.43) | HTR6CA2ALDH1A1SLC40A1 | |
| SCHEMBL8916161 | 0.72 | NR3C1 (0.44) | PGRKDM1ACA2ALDH1A1SLC40A1 | |
| SCHEMBL8917772 | 0.71 | CA1 (0.43) | PGRSCN9ASCN5AKDM1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |