Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918537 | 0.91 | FBP1 (0.33) | TRPV4ALDH1A1FBP1HSD17B10ACLY | |
| SCHEMBL8917798 | 0.84 | MCL1 (0.47) | MCL1ALDH1A1TSHRFBP1RAB9A | |
| SCHEMBL8917242 | 0.84 | PGR (0.34) | ALDH1A1FBP1 | |
| SCHEMBL8919620 | 0.82 | MAPT (0.34) | USP2MAPT | |
| SCHEMBL8916660 | 0.82 | SGK1 (0.33) | MAPT | |
| SCHEMBL8917485 | 0.75 | ALDH1A1 (0.49) | MCL1ALDH1A1TSHRRAB9A | |
| SCHEMBL8918579 | 0.73 | ALDH1A1 (0.40) | MCL1ALDH1A1TSHRRAB9A | |
| SCHEMBL8921166 | 0.72 | CA2 (0.33) | FBP1 | |
| SCHEMBL8916165 | 0.72 | LMNA (0.40) | MCL1ALDH1A1TSHRFBP1 | |
| SCHEMBL8917749 | 0.71 | FBP1 (0.32) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |