Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.40 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.40 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.40 |
| ▸ | P2RY4 known ✓ | P51582 | 4/20 | 0.38 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | P2RY12 known ✓ | Q9H244 | 5/20 | 0.37 |
| ▸ | P2RY2 known ✓ | P41231 | 3/20 | 0.37 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790851 | 0.91 | ENPP2 (0.41) | RAD51CA12CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL16010169 | 0.90 | ENPP2 (0.41) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL7897023 | 0.90 | ENPP2 (0.41) | RAD51CA12CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL16010164 | 0.90 | ENPP2 (0.41) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL6477656 | 0.88 | RAD51 (0.42) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL16671688 | 0.88 | RAD51 (0.49) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL1169584 | 0.87 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL893765 | 0.87 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL29737199 | 0.87 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL30532269 | 0.87 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005950-B2 | Pectate lyase variants | NOVOZYMES A/S (DK) | 2015-04-14 | — | — | US | disclosed |
| EP-1433839-B2 | Optimised wash and cleaning compositions for an improved bleaching effect at low temperatures | DALLI WERKE GMBH & CO KG (DE) | 2015-04-01 | — | — | EP | disclosed |
| US-20140005093-A1 | Pectate Lyase Variants | NOVOZYMES A/S (DK) | 2014-01-02 | — | — | US | disclosed |
| US-8563290-B2 | Pectate lyase variants | NOVOZYMES A/S (DK) | 2013-10-22 | — | — | US | disclosed |
| US-8501448-B2 | Family 44 xyloglucanases | NOVOZYMES A/S (DK) | 2013-08-06 | — | — | US | disclosed |
| US-20130086755-A1 | Family 44 Xyloglucanases | NOVOZYMES A/S (DK) | 2013-04-11 | — | — | US | disclosed |
| EP-2285944-B1 | LIQUID DETERGENT COMPOSITIONS | NOVOZYMES AS (DK) | 2013-03-13 | — | — | EP | disclosed |
| US-8354263-B2 | Family 44 xyloglucanases | NOVOZYMES A/S (DK) | 2013-01-15 | — | — | US | disclosed |
| US-20130012424-A1 | Pectate Lyase Variants | NOVOZYMES A/S (DK) | 2013-01-10 | — | — | US | disclosed |
| US-8288144-B2 | Mutants with improved detergent stability; use in the textile, detergent and cellulose fiber processing industries | NOVOZYMES A/S (DK) | 2012-10-16 | — | — | US | disclosed |
| EP-0118191-A1 | Laundry additive compositions | THE PROCTER & GAMBLE COMPANY (US) | 1984-09-12 | — | — | EP | disclosed |
| US-4448699-A | PROTECTION TO MACHINE ENAMEL COATED SURFACES | THE PROCTER & GAMBLE COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| EP-0098129-A1 | Detergent additive product | THE PROCTER & GAMBLE COMPANY (US) | 1984-01-11 | — | — | EP | disclosed |
| EP-0095904-A1 | Detergent liquors and compositions for use therein | THE PROCTER & GAMBLE COMPANY (US) | 1983-12-07 | — | — | EP | disclosed |
| US-4399049-A | PARTICLES EXTRUDED WITH ETHOXYLATED NONIONIC SURFACTANT; STORAGE STABILITY; RABID DISPERSION; LAUNDERING | THE PROCTER & GAMBLE COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0085448-A1 | Detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1983-08-10 | — | — | EP | disclosed |
| US-4333862-A | Detergent compositions comprising mixture of cationic, anionic and nonionic surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0051986-A2 | Detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1982-05-19 | — | — | EP | disclosed |
| US-4321165-A | Detergent compositions comprising cationic, anionic and nonionic surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| US-4264466-A | LAUNDRY DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1981-04-28 | — | — | US | disclosed |