Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782827 | 0.84 | F10 (0.46) | F10ALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8942753 | 0.83 | PARP1 (0.52) | MTNR1AMTNR1BALDH1A1KMT2A | |
| SCHEMBL8942585 | 0.81 | MEN1 (0.42) | F10ALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8942429 | 0.79 | PARP10 (0.45) | MTNR1AMTNR1BALDH1A1KMT2A | |
| SCHEMBL8942395 | 0.77 | ALOX5 (0.47) | ALDH1A1 | |
| SCHEMBL203154 | 0.76 | PARP1 (0.58) | FURINKMT2AGPR174 | |
| SCHEMBL8942408 | 0.76 | TNKS (0.39) | ALDH1A1KMT2A | |
| SCHEMBL8942712 | 0.76 | PARP14 (0.45) | KMT2A | |
| SCHEMBL8942679 | 0.76 | MAPT (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL8942628 | 0.76 | SCN7A (0.43) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |