Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945941 | 0.82 | RIPK1 (0.39) | RIPK1MAPTOPRK1LMNACYP2D6 | |
| SCHEMBL8945878 | 0.81 | RIPK1 (0.39) | MMP1MMP9MMP13RIPK1OPRK1 | |
| SCHEMBL8945899 | 0.80 | OPRK1 (0.41) | MMP1MMP9MMP13RIPK1MAPT | |
| SCHEMBL8945836 | 0.80 | OPRK1 (0.41) | RIPK1MAPTOPRK1LMNACYP3A4 | |
| SCHEMBL8945854 | 0.76 | RIPK1 (0.40) | RIPK1MAPTOPRK1CYP3A4CYP2D6 | |
| SCHEMBL8945943 | 0.74 | L3MBTL1 (0.44) | OPRK1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8946105 | 0.71 | RIPK1 (0.38) | MMP1MMP9MMP13RIPK1MMP8 | |
| SCHEMBL1143876 | 0.70 | ALOX5 (0.41) | TP53LMNATSHRCYP2C19RAB9A | |
| Hydrochloric Acid SCHEMBL9482649 | 0.70 | TAAR1 (0.46) | MAPTCYP3A4CYP2D6CYP2C19HPGD | |
| SCHEMBL1883138 | 0.70 | RIPK1 (0.47) | RIPK1MAPTOPRK1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |