Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945920 | 0.82 | MMP1 (0.42) | RIPK1OPRK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8945836 | 0.79 | OPRK1 (0.41) | RIPK1OPRK1RAB9AMMP8LMNA | |
| SCHEMBL8945878 | 0.78 | RIPK1 (0.39) | RIPK1OPRK1MMP8OPRM1OPRD1 | |
| SCHEMBL8945899 | 0.77 | OPRK1 (0.41) | RIPK1OPRK1MMP8OPRM1OPRD1 | |
| SCHEMBL8945854 | 0.75 | RIPK1 (0.40) | RIPK1OPRK1SMN1; SMN2MMP8OPRM1 | |
| SCHEMBL8945943 | 0.74 | L3MBTL1 (0.44) | OPRK1SMN1; SMN2L3MBTL1LMNACYP2D6 | |
| SCHEMBL1883138 | 0.70 | RIPK1 (0.47) | RIPK1OPRK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8945931 | 0.68 | MEN1 (0.49) | RIPK1NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8946105 | 0.68 | RIPK1 (0.38) | RIPK1MMP8 | |
| SCHEMBL8945937 | 0.67 | ALOX5 (0.36) | RIPK1OPRK1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |