Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945836 | 0.82 | OPRK1 (0.41) | RIPK1OPRK1ALDH1A1MMP8MAPT | |
| SCHEMBL8945943 | 0.79 | L3MBTL1 (0.44) | OPRK1CYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL8945920 | 0.76 | MMP1 (0.42) | RIPK1OPRK1MMP8CYP2D6CYP2C19 | |
| SCHEMBL8945941 | 0.75 | RIPK1 (0.39) | RIPK1OPRK1ALDH1A1MMP8CYP2D6 | |
| SCHEMBL8945899 | 0.75 | OPRK1 (0.41) | RIPK1OPRK1ALDH1A1MMP8MAPT | |
| SCHEMBL8945878 | 0.74 | RIPK1 (0.39) | RIPK1OPRK1MMP8OPRM1OPRD1 | |
| SCHEMBL28622173 | 0.72 | ALDH1A1 (0.46) | CYP1A2ALDH1A1CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL9322413 | 0.72 | KDM4E (0.51) | CYP1A2ALDH1A1CYP2D6CYP2C19MAPT | |
| SCHEMBL1883138 | 0.70 | RIPK1 (0.47) | RIPK1OPRK1CYP1A2ALDH1A1MMP8 | |
| SCHEMBL25587532 | 0.69 | CYP2C19 (0.46) | CYP1A2ALDH1A1CYP2D6CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |