Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945836 | 0.87 | OPRK1 (0.41) | LMNAADRB3OPRK1CYP3A4 | |
| SCHEMBL8945854 | 0.79 | RIPK1 (0.40) | SMN1; SMN2OPRK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8945899 | 0.78 | OPRK1 (0.41) | ADRB3OPRK1 | |
| SCHEMBL8945920 | 0.74 | MMP1 (0.42) | LMNAHPGDSMN1; SMN2OPRK1CYP3A4 | |
| SCHEMBL8945941 | 0.74 | RIPK1 (0.39) | L3MBTL1LMNAHTTSMN1; SMN2OPRK1 | |
| SCHEMBL8866135 | 0.73 | CYP1A2 (0.63) | L3MBTL1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8945878 | 0.73 | RIPK1 (0.39) | OPRK1 | |
| SCHEMBL19464263 | 0.72 | TBXAS1 (0.55) | EPHX2CYP2C9CYP2C19 | |
| SCHEMBL6954926 | 0.72 | ITGB3 (0.52) | L3MBTL1LMNAHPGDHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6954064 | 0.71 | ITGB3 (0.51) | L3MBTL1LMNAHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |