Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14577808 | 0.87 | LMNA (0.49) | LMNASMN1; SMN2CNR1MEN1KMT2A | |
| SCHEMBL903037 | 0.86 | POLB (0.41) | LMNASMN1; SMN2CNR1MEN1KMT2A | |
| SCHEMBL11037053 | 0.86 | CNR1 (0.47) | LMNASMN1; SMN2CNR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11882877 | 0.85 | LMNA (0.48) | LMNASMN1; SMN2CNR1MEN1KMT2A | |
| SCHEMBL11236184 | 0.85 | NPC1 (0.50) | LMNASMN1; SMN2CNR1MEN1KMT2A | |
| SCHEMBL7940916 | 0.84 | POLB (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL10015687 | 0.84 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2CNR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL13584911 | 0.83 | NPC1 (0.48) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13400831 | 0.83 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2ALDH1A1EPHX1 | |
| Chlorhexidine SCHEMBL1898352 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149042-B2 | Antiseptic solution of di(4-chloro-phenyldiguanido) compound and process therefor | MEDICHEM, S.A. (ES) | 2015-10-06 | — | — | US | disclosed |
| US-9149042-B2 | Antiseptic solution of di(4-chloro-phenyldiguanido) compound and process therefor | MEDICHEM, S.A. (ES) | 2015-10-06 | — | — | US | disclosed |
| US-20120238635-A1 | Antiseptic Solution of Di(4-Chloro-Phenyldiguanido) Compound and Process Therefor | COMBINO PHARM, S.L. (ES) | 2012-09-20 | — | — | US | disclosed |
| US-20120237452-A1 | Antiseptic Solution of Di(4-Chloro-Phenyldiguanido) Compound And Process Therefor | COMBINO PHARM, S.L. (ES) | 2012-09-20 | — | — | US | disclosed |
| US-20120238635-A1 | Antiseptic Solution of Di(4-Chloro-Phenyldiguanido) Compound and Process Therefor | COMBINO PHARM, S.L. (ES) | 2012-09-20 | — | — | US | disclosed |
| US-20120237452-A1 | Antiseptic Solution of Di(4-Chloro-Phenyldiguanido) Compound And Process Therefor | COMBINO PHARM, S.L. (ES) | 2012-09-20 | — | — | US | disclosed |
| US-8188068-B2 | Bridged polycyclic compound based compositions for coating oral surfaces in pets | ALLACCEM, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8153618-B2 | Bridged polycyclic compound based compositions for topical applications for pets | ALLACCEM, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100098659-A1 | COMPOSITIONS AND METHODS FOR TREATING MATRIX METALLOPROTEINASE 9 (MMP9)-MEDIATED CONDITIONS | REVALESIO CORPORATION (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100098659-A1 | COMPOSITIONS AND METHODS FOR TREATING MATRIX METALLOPROTEINASE 9 (MMP9)-MEDIATED CONDITIONS | REVALESIO CORPORATION (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100016270-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR CONTROLLING CHOLESTEROL LEVELS | ALLACCEM, INC. | 2010-01-21 | — | — | US | disclosed |
| US-20090054528-A1 | Bridged polycyclic compound based compositions for coating oral surfaces in pets | ALLACCEM, INC. | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054528-A1 | Bridged polycyclic compound based compositions for coating oral surfaces in pets | PAICS, SLC16A8, CAD | LMNA 2168/4885SMN1; SMN2 1523/4885CNR1 471/4885 |
| US-20100016270-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR CONTROLLING CHOLESTEROL LEVELS | PCSK9, HMGCR, CETP | LMNA 234/4885SMN1; SMN2 1707/4885CNR1 769/4885 |
| US-20120238635-A1 | Antiseptic Solution of Di(4-Chloro-Phenyldiguanido) Compound and Process Therefor | QDPR, DDT, SLC6A11 | LMNA 4870/4885SMN1; SMN2 4736/4885CNR1 657/4885 |
| US-20120237452-A1 | Antiseptic Solution of Di(4-Chloro-Phenyldiguanido) Compound And Process Therefor | QDPR, DDT, SLC6A11 | LMNA 4870/4885SMN1; SMN2 4736/4885CNR1 657/4885 |
| US-20100098659-A1 | COMPOSITIONS AND METHODS FOR TREATING MATRIX METALLOPROTEINASE 9 (MMP9)-MEDIATED CONDITIONS | MMP9, MMP14, MMP10 | LMNA 373/4885SMN1; SMN2 104/4885CNR1 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.