Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963675 | 0.89 | TACR1 (0.36) | OPRM1OPRD1ADRB1TACR1PIN1 | |
| SCHEMBL8963737 | 0.88 | OPRM1 (0.38) | OPRM1OPRD1ADRB1TACR1PRMT5 | |
| SCHEMBL8963561 | 0.87 | SLC6A2 (0.47) | SLC6A2SLC6A4OPRM1OPRD1ADRB1 | |
| SCHEMBL8964138 | 0.86 | SLC6A4 (0.38) | SLC6A2SLC6A4OPRM1OPRD1ADRB1 | |
| SCHEMBL8964068 | 0.86 | PRMT5 (0.44) | SLC6A2SLC6A4OPRM1OPRD1PRMT5 | |
| SCHEMBL8963580 | 0.86 | PRMT5 (0.40) | SLC6A2SLC6A4OPRD1TACR1PRMT5 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.85 | PRMT5 (0.40) | SLC6A2SLC6A4OPRD1TACR1PRMT5 | |
| SCHEMBL8963691 | 0.85 | TACR1 (0.34) | SLC6A4OPRD1TACR1PRMT5 | |
| SCHEMBL8964088 | 0.84 | OPRD1 (0.37) | OPRM1OPRD1ADRB1PRMT5HTR1A | |
| SCHEMBL8963505 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A4ADRB1TACR1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |