Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 4/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964088 | 0.92 | OPRD1 (0.37) | OPRM1OPRD1PRMT5HTR1AHTR7 | |
| SCHEMBL8964068 | 0.92 | PRMT5 (0.44) | OPRM1OPRD1PRMT5HTR1AHTR7 | |
| SCHEMBL8963532 | 0.88 | SLC6A2 (0.41) | OPRM1OPRD1PRMT5HTR1AHTR7 | |
| SCHEMBL8963637 | 0.87 | MAPK13 (0.37) | OPRM1OPRD1PRMT5HTR1AHTR7 | |
| SCHEMBL8963516 | 0.87 | CHEK2 (0.42) | OPRM1OPRD1PRMT5HTR1AHTR7 | |
| SCHEMBL8963580 | 0.87 | PRMT5 (0.40) | OPRD1PRMT5KMT2AMEN1TACR1 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.86 | PRMT5 (0.40) | OPRD1PRMT5KMT2AMEN1TACR1 | |
| SCHEMBL8963820 | 0.85 | HDAC6 (0.34) | OPRM1OPRD1HPGD | |
| SCHEMBL8963505 | 0.82 | SLC6A2 (0.41) | PRMT5HTR1AHTR7HTR6HTR3A | |
| SCHEMBL8963675 | 0.82 | TACR1 (0.36) | OPRM1OPRD1PRMT5HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |