Methacrylic Acid

Methacrylic Acid

SCHEMBL8965245

C=C(C)C(=O)O.C=C(C)C(=O)OCC1CO1.C=CC(=O)Oc1ccc(C(=O)C=Cc2ccc(OC)c(C)c2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TNFRSF1A P19438 2/20 0.43
MAPT P10636 4/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
ABCG2 Q9UNQ0 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.40
RECQL P46063 1/20 0.40
RAB9A P51151 1/20 0.40
CXCL12 P48061 1/20 0.39
NFKB1 P19838 4/20 0.39
NFKB2 Q00653 4/20 0.39
RELA Q04206 4/20 0.39
MAPK1 P28482 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965834 0.98 TNFRSF1A (0.45) TNFRSF1AMAPTKDM4ELMNAABCG2
SCHEMBL8965374 0.82 F3 (0.44) TNFRSF1AMAPTLMNAMEN1KMT2A
SCHEMBL8965407 0.82 TNFRSF1A (0.62) TNFRSF1AMAPTKDM4ELMNAABCG2
SCHEMBL8965410 0.82 TNFRSF1A (0.62) TNFRSF1AMAPTKDM4ELMNAABCG2
SCHEMBL30467144 0.82 TNFRSF1A (0.62) TNFRSF1AMAPTKDM4ELMNAABCG2
Methacrylic Acid SCHEMBL8965877 0.82 MAOB (0.40) MAPTABCG2ALDH1A1
Methacrylic Acid SCHEMBL8965210 0.81 F3 (0.39) TNFRSF1AMAPTLMNAMEN1KMT2A
Methacrylic Acid SCHEMBL8965253 0.75 ALDH1A1 (0.45) MAPTKDM4ELMNAMEN1KMT2A
SCHEMBL4725650 0.74 TNFRSF1A (0.76) TNFRSF1AMAPTKDM4ELMNAABCG2
Methacrylic Acid SCHEMBL8964995 0.73 MAOB (0.39) MAPTABCG2KMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 TNFRSF1A 3485/4885MAPT 3512/4885KDM4E 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.